Abstract
Summary
1. The D- and L-isomers of amidone and isoamidone inhibit the cholin-esterases of rat brain and dog serum. 2. These drugs exert a greater inhibitory action on serum cholinesterase than on brain cholin-esterase. 3. The L-isomers are more effective than the D-isomers in inhibiting these enzymes. 4. The greatest difference in effect between the D- and L-isomers was observed in experiments on the effect of D- and L-iso-amidone on brain cholinesterase.
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