Abstract
Summary and Conclusion
The performance of agglutination tests, using the blood cells of mice of 5 inbred strains and 8 types of F1 and F2 hybrid mice, have shown that human sera can be differentiated, apart from the usual intra-group reactions, by their ability to agglutinate mouse erythrocytes. The differentiation of human sera on this basis depended on the presence or absence of a specific agglutinin (Mo agglutinin). It was found to bear no specific relationship to either the A-B-0 blood groups or the Rh factor. Five of the 37 human sera tested (approximately 14%) did not contain the Mo agglutinin. Mouse erythrocytes adsorbed the Mo agglutinin but not α and β agglutinins or the rabbit cell agglutinin. Human erythrocytes of the a and β group and rabbit red cells adsorbed their specific agglutinins, but not the Mo agglutinin.
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