Abstract
Summary
In various buffers. MM virus was stable at room temperature only at neutral or alkaline reactions. When diluted virus was exposed at approximately pH 1.0 to neutrality the infectivity was diminished within twenty-four hours. There was a slower decrease in virus titer at pH 9 to 10. At pH 7 to 9, the virus was found to be stable for more than seven days. The deleterious effect of unfavorable pH was less for concentrated virus suspensions. MM virus was apparently more stable in distilled water acidified with hydrochloric or acetic acid than in acidified physiologic saline or in veronal-acetate buffer solutions of approximately the same pH value.
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