Abstract
Summary
1. In confirmation of Chase's studies, the tuberculin type of hypersensitivity has been transferred passively to normal, unsensitized guinea pigs by injection of the cells of peritoneal exudate, lymph nodes, spleen, and whole blood of tuberculin-sensitive guinea pigs. The passively conferred sensitivity lasted 4 or 5 days.
2. The transfer of sensitivity by injection of whole blood taken with other observations suggests that the white cells of the circulating blood may participate more widely than previously believed in immunological phenomena.
3. The positive results employing suspensions containing 95% of lymphocytes suggest that this cell type may be of great importance in the transfer of sensitivity.
Get full access to this article
View all access options for this article.