Abstract
Summary
1. A method of purification of resin Amberlite IR-lOO was devised. When blood was treated with the purified resin a decreased sedimentation rate was found, with morphological, chemical, and physical properties otherwise practically unmodified.
2. Of the factors involved in blood coagulation, prothrombin, fibrinogen and the labile factor described by Quick apparently were not appreciably altered by the decalcification with Amberlite, With optimal recalcification, the clotting time of the treated blood was much shorter than that of native blood, but this is also true for oxalated and citrated blood.
3. A reduced antithrombin activity was observed in Amberlite plasma upon incubation with “full strength” thrombin. Since citrated plasma responded similarly, the be- of decalcification of the 3 agents. haviour may be linked with the mechanism
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