Abstract
Summary
The influence on lactation of various gonadotrophins of pituitary and chorionic origin has been studied in laetating rats. P.M.S. had a strong inhibitory effect resulting in the death of most of the young; A.P.L. had a slight effect on the growth curve of the young, while an anterior pituitary preparation was inactive. From histologic studies of ovary, vagina and uterus it is suggested that the activity of P.M.S. is due to a high level of estrogens and progesterone.
Our thanks are due to Dr. S. Cook of Ayerst, McKenna and Harrison, Ltd. (Montreal) for A.P.L. and P.M.S., to Dr. H. Jensen of Hormones Corporation (Montreal) for L.A.P., and to Dr. E. MeCullagh of the Schering Corporation
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