Abstract
Summary and Conclusions
Using appropriate experimental conditions, a virulent human strain of M. tuberculosis has been found to undergo partial lysis in the presence of high concentrations of penicillin.
Small inocula of tubercle bacilli are highly susceptible to concentrations of penicillin as low as 1 unit per cc in the Tween-albumin medium. In the oleic acid-albumin medium, penicillin in a concentration of 100 units per cc causes no inhibition of growth, even with the smallest inocula
Preliminary experiments indicate that in both the solid and liquid oleic acid-albumin medium, penicillin in concentrations of 50 to 100 units per cc may prove a valuable adjunct in culturing tubercle bacilli from contaminated materials.
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