Abstract
Summary
Albino rats were made hypothyroid by treatment with thiouracil and hyperthyroid by administration of thyroxin. After 60 days of treatment, gastrocnemiussoleus muscles of throxin treated animals showed weakness and increased susceptibility to fatigue through motor nerve stimulation. Thiouracil treatment for a like period of time resulted in no loss of muscle weight or strength, but did produce a slight increase in susceptibility to fatigue by indirect stimulation.
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