Abstract
Summary
The clear protein and cell-free urine from normal men and women and from hemophilic men has thromboplastic activity when tested on normal and hemophilic blood. The thromboplastin in dialysed and lyophilized urine seems more resistant to heat than that in fresh urine. The lyophilized dialysed urine residue has a clot accelerating action on hemophilic blood in vitro and in vivo. The clots which form in the ureter of hemophilics with hematuria are probably due to contact of the extravasated blood with the thromboplastin of the urine.
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