Abstract
Summary
Chicks deprived of pteroylglutamic acid (folic acid) for the first 4 weeks of life respond dramatically to a single administration of the vitamin given either orally or intramuscularly. The reticulocyte response preceded hemoglobin increase and reached a peak 4 to 6 days following administration. Intramuscular injection of pteroylglutamic acid was more than twice as effective as the same amount administered orally. The hemoglobin increase in 7 days was proportional to the amount of pteroylglutamic acid administered either by mouth or by intramuscular injection.
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