Hypersensitivity to Egg White in the Rat. ∗

Abstract

Summary

In the rat a single intravenous or intraperitoneal injection of egg white elicits a reaction characterized by hyperemia, followed by edema of the face, tongue and paws. Although only these regions respond, they are not necessarily affected to an equal extent. Continued injections of the same dose produce variable reactions in the same animals but there is no acquired tolerance. Age does not play a great influence, but females seem less sensitive than males.