Abstract
Summary
Streptomycin in amounts of from 0.5 to 2.0 mg injected into infected embryonated eggs has a definite slight inhibitory action on the growth of R. prowazeki. In the case of R. rnooserl, 2.0 mg of streptomycin had a. small but significant effect. With R. orientalis, a dose of 2.0 mg per egg appeared to have no significant effect on the multiplication of the rickettsiae. By contrast, appropriate doses of PABA (5.5 mg per egg for R. prowazeki, and 11.0 mg per egg for R. mooseri and R. orientalis) produced a striking inhibition of growth, reducing the numbers of viable rickettsiae by 10,000 to over 10,000,000 times as compared with untreated controls.
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