Abstract
Summary
In the preparation of antiorgan sera the administration of small amounts of antigen (spleen and bone marrow) was found more effective than the rapid immunization of rabbits with massive antigen dosage. A single injection of the antigen 30-40 days after the last dose gives rise to an anamnestic response of the host and to a serum of higher potency. This can be evaluated by complement fixation titres and by the outgrowth of tissue explants exposed to the action of the “anamnestic” serum.
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