Abstract
Summary
Intraperitoneal injections of urethane (1 cc of a 10% aqueous solution per 100 g of body weight) almost wholly does away with all stages of mitosis for a period of 8 to 12 hours, judging from counts of mitotic figures in sections of the corneal epithelium from rats and mice. In a later experiment, lung tumors of adenomatous type appeared in 75 of 86 animals treated with urethane, but what, if any, connection there is between the interference of this drug with mitosis and its causation of lung tumors is not evident.
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