Abstract
Summary
The above elidence indicates that pteroylglutamic acid, or its conjucated torm does not act directly in an unaltered, tate upon primitive red cells to mature them, nhereai a highly potent antipernicious anemia liver preparation appears to cause a maturation comparable to that observed in the presence of serum. A single sample of serum from a patient haling pernicious aneinld in relapse appeared to lack the maturation factor found in normal human and ration. Pteroqldutamic acid failed to increase the maturation of bone marrow cells suspended in this serum
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