Abstract
Summary
In the normal dog fasted 3 or 5 days, the organs drained by the portal vein remove significant amounts of glucose and acetone bodies, but have no consistent effectupon the blood lactic acid. In the depancreatized dog, 3 to 7 days after the with-drawal of food and insulin, these organs continue to remove statistically significant quantities of glucose and increase their removal of acetone bodies. Under these conditions they add lactic acid to the blood. If the glucose removed by the gastrointestinal tract of the depancreatized dog and not returned to the blood as lactate is oxidized, it will account for approximately 876 of the animal's resting metabolism.
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