Abstract
Summary and Conclusions
The incubation of liver extracts or pteroyl glutamic acid with certain dog blood sera caused an increase in the cholinesterase activity of the sera. From such experiments it was estimated that 1 mg of pteroyl glutamic acid was roughly equal to 1 ± 0.5 U.S.P. unit of the liver extracts examined, in cholinesterase activity potentiating power.
The administration of liver extracts and pteroyl glutamic acid to dogs in which the serum cholinesterase had been greatly depleted by diisopropyl-fluorophosphate injections, caused more rapid regeneration of this enzyme activity than was observed in untreated control animals.
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