Abstract
Summary
1. The neuromuscular responses and general behavior of white rats were studied, (1) in a circular maze, (2) on animals trained to walk a tightly-stretched horizontal rope, and (3) on animals trained to climb a vertically-stretched rope.
2. Injections of small quantities of pemphigus sera in these rats produced a definite depression of performance in all 3 tests, while control experiments with normal sera did not affect the rats adversely.
3. These findings corroborate the authors'experiments with pemphigus sera on plants and indicate that this disease is a systemic, rather than a cutaneous one, as is indicated by the toxic effects exerted by the blood serum of patients with pemphigus.
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