Abstract
Conclusions
The previous observation that only a slight and inconstant prolongation of penicillin blood levels is obtained by the use of a water-in-oil emulsion is confirmed. The present findings suggest further that a substantial increase in the intramuscular dose of penicillin in the same volume of saline will give considerably higher and better sustained plasma levels than the smaller dose given in a water-in-oil emulsion and the disadvantages of the latter method are thus avoided.
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