Growth Retardation and Corneal Vascularization with Tyrosine and Phenylalanine in a Purified Diet

Abstract

Summary

The addition of 1% dl-phenylalanine and 1% l(-) tyrosine to a purified diet containing 10% casein produced growth retardation and external lesions. Phenylalanine is converted to tyrosine in the animal and so may add to the effect of the tyrosine. The addition of relatively large amounts of nicotinic acid or l(-)tryptophane will appre ciably alleviate the deleterious effects of these amino acids.