Abstract
Summary
A saline-soluble portion of larvae of Trichinella spiralis has been compared as to its electrophoretic characteristics and production of allergic response in sensitized animals with other fractions, prepared by-acidification and by heating. Each of the 3 fractions separated into 3 electrophoretic components in addition to an incompletely separated portion associated with component 2 and a fast moving heterogeneous mixture. In the primary extract the heterogeneous mass represented more than 60% of the total concentration. Either acid or heat treatment removed practically all of this mixture. More material was precipitated by heating than by acidification. The 3 fractions were diluted on the basis of the original dry weight of larvae and intradermal reactions compared. There was no apparent difference in the area of edema produced by the primary extract and the acid-soluble fraction. The heat-treated allergen caused slightly less reaction than the other 2. There is an indication that the allergen is associated with component 1.
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