Abstract
Summary and Conclusions
Experiments were undertaken in unanesthetized dogs to study the effect of distention of a segment of jejunum, in the form of a Thiry fistula, upon the tonus of the cardia and upon the relaxation of the cardia resulting from swallowing or from esophageal distention. It was found that the cardia is not easily influenced by changes in jejunal pressure. However, repeated moderate distention of a short jejunal segment may produce a decrease in tonus of the cardia without evidences of nausea or other distress. Secondly, it was found that distention of a jejunal segment does not alter the relaxation-contraction pattern of the cardia which is produced by the swallowing act or by esophageal distention.
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