Abstract
Summary
A hemagglutinin appears in the amniotic fluid of normal chick embryos between the 11th and 13th days of incubation. The erythrocytes of 13 of 18 species tested are agglutinated. Mouse and rabbit cells are agglutinated to the highest titer. Guinea pig cells are also agglutinated, but chicken cells are not. Hemagglutination occurs best in the cold.
The hemagglutinin is associated with the globulin fraction of egg white. It gains access to the amniotic fluid when the content of the albumin sac ruptures into the amniotic sac between the 11th and 13th days of development of the embryo.
The hemagglutinin is thermolabile. It is adsorbed by mouse but not by chicken erythrocytes.
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