Abstract
Summary
Bile capillaries show distinct phosphatase activity in the normal dog liver. This property can be used for their microscopic demonstration. After ligation of the common bile duct there is not only marked dilatation ot' the bile capillaries but also apposition of phosphatase around them which increases with the duration of the experiment. The changes in the distribution of alkaline phosphatase in histochemical preparations favor the assumption that the increase of serum phosphatase in liver damage is due. to the inability of the liver cells to excrete the enzyme rather than to increased production in the liver itself.
Get full access to this article
View all access options for this article.