Abstract
Summary
1. A simple method for the preparation of protoporphyrin from blood is described. 2. White rats were injected subcutaneously with protoporphyrin and were found to excrete greatly increased amounts of protoporphyrin in the feces. No urinary protoporphyrin nor increase of urinary coproporphyrin excretion following the injection was noted. Much of the injected protoporphyrin remained at the site of injection. There was no evidence that the rat is able to convert injected protoporphyrin to coproporphyrin. 3. Photosensitization experiments of protoporphyrin-injected white rats to carbon-arc and sunlight were unsuccessful.
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