Abstract
Summary
Eleven ovarian tumors, induced by X-rays have been transmitted in successive passages. Eight were of the granulosa cell types, 2 were luteomas and one was a tubular adenoma. Histological changes indicate that cells of Strain III secrete estrogens. Mice bearing tumors of this strain also have a cavernous dilatation of the sinusoids of liver, spleen and adrenals. In mice bearing large luteoma of Strain IX there is profound atrophy of the adrenal cortex.
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