Blood Chemical Changes Following Intravenous Administration of a Casein Hydrolysate to Human Subjects. ∗

Abstract

Summary

Injection of 45 g of Parenamine intravenously at slow speeds produced an average plasma amino acid N rise of +4.9 mg per 100 cc during the injection with a return to normal in 2 hours. Rises to levels above 10 mg per 100 cc produced by rapid injection may be associated with nausea and vomiting. A progressive though slight rise in blood urea takes place during and after the injection, accompanied by increased urea excretion. Serum inorganic phosphate is lowered during the injection and returns to normal by the end of the injection. Only a negligible drop in CO₂ combining power occurred during the injection. Intravenously injected glucose did not alter the curves produced by the amino acid injection.