Abstract
Summary
Bioassays with chicks have shown that 2,4-dimethyl-3-hydroxy-5-hydroxymethylpyridine is a very potent inhibitor of pyridoxine. Under the conditions of these experiments, two molecules of the inhibitor were sufficient to offset the vitamin activity of one molecule of pyridoxine. This ratio was found to hold for suboptimal and optimal amounts of pyridoxine given to pyridoxine-deficient chicks.
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