Abstract
Summary
High concentrations of nicotinamide exert a synergistic effect upon penicillin inhibition of Staphylococcus aureus. Nicotinic acid was inactive in this respect. No evidence for a reaction between nicotinamide and penicillin could be found. Although the effect of nicotinamide appeared to be general for the 3 strains of staphylococcus tested, no effect could be demonstrated upon either Streptococcus pyogenes or E. coli.
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