Abstract
Summary
1. A method for producing tourniquet shock in rats is described. The method yields graded and reproducible results.
2. The percentage survival of rats to tourniquet shock was progressively decreased as the time of tourniquet application was increased. Following 3% hours of tourniquets 100% of the rats survived, while after 4 hours of tourniquets only 3% survived.
3. Rats which had tourniquets applied for 4 hours with periods of release for 1 to 6 hours, followed by a second application of tourniquets, showed 100% in contrast to 3% survival for those without replacement, while 87.5% survived when the tourniquets were replaced after 7 hours.
4. The degree of hemoconcentration developing in rats in tourniquet shock was approximated by hemoglobin determinations. Increases in hemoglobin ranged between 27 and 52%.
Get full access to this article
View all access options for this article.