Abstract
Summary
A potent penicillin-inactivating substance is produced by penicillin-resistant Staphylococcus aureus but not by penicillin-sensitive strains. The substance is soluble and diffuses readily into both liquid and solid culture medium. The variation of susceptibility to penicillin among various strains of Staphylococcus aureus appears to be associated with a difference in this enzyme formation.
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