Abstract
Summary
The therapeutic effects of sodium sulfadiazine upon Amblystoma embryos, following surgical interruption of the central nervous system, are described. Embryos which may undergo 100% mortality when sterile technic is not employed, will survive when treated for 2 days with a 1% aqueous solution of the drug. There is no evidence of any toxic effect. Treated embryos undergo normal development and at a rate parallel with control embryos kept at the same temperature.
Minimum concentrations of the drug as well as minimum length of treatment necessary to insure survival remain to be determined.
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