Abstract
Summary
Influenza virus B (Lee strain) increases to small degree in the chorio-allantoic fluid of 11-day-old chick embryos incubated for 60 hours at 39°C after inoculation with the virus. Increase was great at 37°C and still greater at 35°C. The pH of the chorio-allantoic fluid of the same embryos descended into the acid region at 39°C; at 37° C the pH remained essentially above 7.0; and at 35°C the reaction was maintained well in the alkaline region. These relations suggest the possibility that the extent of increase of the virus in the chorio-allantoic fluid may be influenced more by the pH of the fluid at the various temperatures than by the temperature per se.
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