Abstract
Summary
Serial propagation of cavian poliomyelitis virus from guinea pig to guinea pig was not significantly influenced by seasonal fluctuation of any sort. However, the mode of transmission of murine poliomyelitis virus from mouse to guinea pig functioned more effectively in the winter than in the summer, as judged by the ratio between paralyzed and non-paralyzed animals. The described phenomenon appears to be due, preponderantly, to cyclic variations in the susceptibility of the guinea pig to the paralyzing effect of the virus when passed by intracerebral injection from one host to another.
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