Comparative Effects of Thromboplastin,Lecithin,and Saline on Mortality of Mice Following Experimental Burn Shock. *

Abstract

Conclusions

1. Mice injected intraperitoneally with a 1% suspension of thromboplastin in isotonic saline solution showed a greater mean survival period than mice injected with either isotonic saline or with a 1% suspension of lecithin in isotonic saline. 2. Mice receiving thromboplastin showed a higher ultimate survival rate than those receiving either lecithin or saline. 3. Analysis by chi² showed a significant difference between thromboplastin and saline but not between lecithin and saline. 4. Intraperitoneal injection of thromboplastin one hour after traumatization of the animals seemed to exert a toxic effect.