Abstract
Summary
Alloxan, injected into pigeons in a single dose of 60 to 125 mg/kg (less than one-half of the diabetogenic dose) sometimes causes a marked elevation of the blood uric acid level and a deposition of sodium urate in the tissues. A conspicuous atrophy of the musculature is observed as a late effect in pigeons which recover from the acute stage of alloxan poisoning. Among several compounds, related to alloxan, only dialuric acid was found to possess a similar effect.
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