Abstract
Summary
An experiment on the transmission of infectious hepatitis has been carried out among 19 volunteers at 2 institutions. At one of the institutions 3 different samples of serum containing the icterogenic agent were inoculated intracutaneously into 5 human subjects, and the disease was produced in 3 after incubation periods of 56 to 70 (avg 64) days.
At another institution other samples of serum and also specimens of feces (and urine) were fed to 9 human subjects, and the disease was produced in 5 after an incubation period of 20 to 84 (avg 37) days by both of these materials.
One case of “naturally acquired” hepatitis has appeared among the institutional personnel 51 days after the beginning of the experiment and 31 days after the appearance of the first experimental case.
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