Abstract
Summary
Gross anatomical malformations can be induced in approximately one-third of the offspring of Wistar rats, if they are fed a deficient diet after maturity. In agreement with previous reports, immature Wistar rats reared on the same diet grow poorly and give little evidence of reaching adult stature and sexual maturity. It has been demonstrated in the literature, however, that immature female rats of either the Sprague-Dawley or Baltimore strains, reared on this diet, attain sexual maturity and produce litters with anomalous young.
It is suggested that the strain differences of rats reared on this diet is expressed rather in the growth and the attainment of sexual maturity than in the production of anomalous offspring.
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