Abstract
Summary and Conclusions
I. Three different types of anuria were observed in these experiments.
1. Anuria following a severe hemorrhage or a reduced blood volume.
2. Anuria following a severe burn.
3. Anuria following a crush injury: this type developed much later, 18 to 36 hours, after injury.
II. The possible factors for the appearance of anuria are: low blood pressure, a reduced blood volume, the hemoglobinemia present in burns, and an unknown substance. This substance may be myohemoglobin or a toxic agent released from the damaged limb.
III. Permanent damage to the kidneys and anuria may develop following crushing or burning, because renal function seems to be most impaired following these two traumatic agents.
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