Action of a Sulfonated Succinic Acid on the Respiratory Metabolism of Frog Tissues. ∗

Abstract

Conclusion

From these observations, it would appear that potassium-sulfon-succinate is not utilized as a substrate nor acts as a reversible carrier. It is capable, however, of inhibiting the catalytic activity of succinate when the latter is present in minute quantities.

This latter inhibition presents an analogy to the activity of para-aminobenzoic acid and the sulfa drugs. Owing to the widespread distribution of succinate in tissues and bacteria, the possible bacteriostatic action is being investigated.