Biochemical Findings in Normal and Trauma-Resistant Rats Following Trauma.

Abstract

Summary

Biochemical changes in the blood and tissues of fed normal rats, and of rats made resistant to trauma, have been studied following the subjection of these animals to trauma in a revolving drum.

NPN rose significantly in the normal, but remained unchanged in the resistant rat.

Blood sugar, and blood and muscle iactic acid, rose in both the normal and resistant, but the difference between the two groups was highly significant. Pyruvic acid rose significantly in the normal, but showed no change in the resistant animal.

While whole blood and serum PO₄ rose 100% in the normal, Ca remained unchanged. There was no change in PO₄ in the resistant rat.

Values for Na and K of blood and muscle, and for liver, heart, and skeletal muscle glycogen showed non-significant differences between normal and resistant animals.