Abstract
Summary
Incorporation of sulfaguanidine at a 0.5% level in purified rations containing p-aminobenzoic acid had no deleterious effects on reproduction in the female albino rat; similarly animals raised on inositol-free rations with or without sulfaguanidine were not inferior in growth, reproductive performance, or gross appearance to litter mates on identical rations with inositol added. Addition of inositol, however, to a purified ration containing sulfaguanidine resulted in marked reduction of fertility, which did not occur if either inositol or sulfaguanidine were omitted from the ration.
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