Abstract
Summary
A study has been made of the fungistatic and fungicidal action of various antibiotic substances upon Ceratostomella ulmi, the causative agent of the Dutch elm disease. Actinomycin and clavacin had a strong effect upon this fungus, penicillin and streptothricin had no effect at all, and other substances fell between.
The antifungal activities of clavacin and especially of actinomycin could be partly overcome by certain nutrients in the medium, especially peptone. Whether this is due to the pyridoxine content, to some other neutralizing effect or to a nutrient effect of the peptone is still to be determined.
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