Abstract
Conclusions
Thiourea, in addition to effecting thyroid enlargement and a decline in the B.M.R., produces in appropriate doses, rapid and fatal pulmonary edema in adult rats. No necessary relation between these two reactions has been demonstrated. The immature rat is much less susceptible to the pulmonary edema and more susceptible to the thyroid enlargement produced by this compound. On a weight basis it tolerates 50 times the lethal dose for adult rats.
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