Abstract
Summary
In continuation of previous studies, the tocopherol level in the serum of patients with amyotrophic lateral sclerosis and with miscellaneous myopathies was found to average 0.67 and 0.61 mg/10O ml respectively. The response to daily oral administration of 75 to 740 mg tocopherol runs parallel to the dosage and attains levels of more than 2.0 mg/100 ml serum, Temporary favorable effects on the clinical status are only found with doses over 200 mg tocopherol per diem. The spinal, fluid does not contain tocopherol.
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