Studies on Muscle and Nerve in Biotin-Deficient Rats. ∗

Abstract

Summary

At no stage of biotin deficiency was the capacity of the motor nerve to elicit tensin in its muscle found to be impaired. Only in the case of animals which were allowed to approach terminal states was there a reduction in then strength of the skeletal muscle. The rates of neuromuscular regeneration following denervation by nerve crush were not significantly different from those found for control animals on adequate diets.