Abstract
Conclusions
An extension was made of an earlier survey of bacterial substances inducing hemorrhage in implanted mouse tumors. It was found that with a few exceptions gram-negative forms induced tumor-hemorrhage, while this property, with one exception, was lacking in the gram-positives. An interesting example was the induction of hemorrhage by the photosynthetic gram-negative purple bacterium Rhodospirillum rubrum. It is concluded that toxins inducing tumor-hemorrhage, and probably bound up in the complex O antigens, are characteristic of gram-negative bacteria.
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