Effect of Thymoxyethyldiethylamine on Various Pain Thresholds with Special Reference to Referred Pain. ∗

Abstract

Observations that the phenol ether, thymoxyethyldiethylamine, administered to unanesthetized dogs produced a generalized elevation of the cutaneous threshold for pain stimuli without evident signs of central narcosis 1 suggested to the authors its possible utility in the experimental study of visceral pain.

Method. Adult untrained dogs were used. The threshold for pain was determined by electrical stimuli supplied from a Harvard inductorium with 4.5 v on the primary circuit.