Abstract
Summary
A method for the study of skin histamine has been described. The histamine equivalent of skin extracts obtained by this method has been shown to increase following injection of histamine into the skin and following burning or chemically irritating the skin. That the substance studied is closely related to histamine has been shown by several tests. Using the method described, experiments have given suggestive evidence that histamine may be liberated in the abdominal skin upon the application of electrodes to and stimulation of the splanchnic nerve.
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