Abstract
Summary
An objective method for the determination of circulation time is presented, which appears to have many advantages over previous methods with respect to accuracy, safety and facility to obtain recorded data. The use of an intravenously injected dye and a light source transmitted through animal tissue to a photoelectric cell, makes determinations possible, by noting the deflection of the needle in a sensitive galvanometer or other sensitive measuring device. The time elapsing between the injection of the dye and the deflection of the needle is the circulation time. Under experimental conditions, the normal circulation time ranged from 9 to 16 seconds, and in decompensated cardio-vascular disease as high as 45 seconds was recorded.
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